Pharmacological Reviews: 65 (1) (2024)

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January 01, 2013; Volume 65,Issue 1

Review Articles

  • A Modern Understanding of the Traditional and Nontraditional Biological Functions of Angiotensin-Converting Enzyme

    Kenneth E. Bernstein, Frank S. Ong, Wendell-Lamar B. Blackwell, Kandarp H. Shah, Jorge F. Giani, Romer A. Gonzalez-Villalobos, Xiao Z. Shen and Sebastien Fuchs

    Rhian M. Touyz, ASSOCIATE EDITOR, Department of Biomedical Sciences and Department of Pathology and Laboratory Medicine, Cedars-Sinai Medical Center, Los Angeles, California

    Pharmacological Reviews January 2013, 65 (1) 1-46; DOI: https://doi.org/10.1124/pr.112.006809

  • CC Chemokine Receptors and Chronic Inflammation—Therapeutic Opportunities and Pharmacological Challenges

    Gemma E. White, Asif J. Iqbal and David R. Greaves

    Christopher J. Garland, ASSOCIATE EDITOR, Sir William Dunn School of Pathology, University of Oxford, Oxford, United Kingdom

    Pharmacological Reviews January 2013, 65 (1) 47-89; DOI: https://doi.org/10.1124/pr.111.005074

  • Homeoprotein Signaling in Development, Health, and Disease: A Shaking of Dogmas Offers Challenges and Promises from Bench to Bed

    Julien Spatazza, Elizabeth Di Lullo, Alain Joliot, Edmond Dupont, Kenneth L. Moya and Alain Prochiantz

    Glenda E. Gillies, ASSOCIATE EDITOR, Development and Neuropharmacology Group (J.S., E.D.L., K.L.M., A.P.), and Cell Biology of Homeoproteins Group (A.J., E.D.), College de France, Centre for Interdisciplinary Research in Biology, CNRS UMR 7241/INSERM U1050, Labex Memolife, PSL Research University, Paris, France

    Pharmacological Reviews January 2013, 65 (1) 90-104; DOI: https://doi.org/10.1124/pr.112.006577

  • Therapeutic Potential of Mood Stabilizers Lithium and Valproic Acid: Beyond Bipolar Disorder

    Chi-Tso Chiu, Zhifei Wang, Joshua G. Hunsberger and De-Maw Chuang

    David R. Sibley, ASSOCIATE EDITOR, Molecular Neurobiology Section, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland

    Pharmacological Reviews January 2013, 65 (1) 105-142; DOI: https://doi.org/10.1124/pr.111.005512

  • The Flinders Sensitive Line Rat Model of Depression—25 Years and Still Producing

    David H. Overstreet and Gregers Wegener

    Lynette C. Daws, ASSOCIATE EDITOR, Department of Psychiatry & Center for Alcohol Studies University of North Carolina at Chapel Hill, Chapel Hill, North Carolina (D.H.O.); Centre for Psychiatric Research Aarhus University & Aarhus University Hospital, Risskov, Denmark (G.W.) and Unit for Drug Research and Development, School of Pharmacy (Pharmacology), North-West University, Potchefstroom, South Africa (G.W.)

    Pharmacological Reviews January 2013, 65 (1) 143-155; DOI: https://doi.org/10.1124/pr.111.005397

  • Integrating Optogenetic and Pharmacological Approaches to Study Neural Circuit Function: Current Applications and Future Directions

    Garret D. Stuber and Alex O. Mason

    Annette C. Dolphin, ASSOCIATE EDITOR, Departments of Psychiatry & Cell Biology and Physiology, UNC Neuroscience Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina

    Pharmacological Reviews January 2013, 65 (1) 156-170; DOI: https://doi.org/10.1124/pr.111.005611

  • The Pharmacology of l-DOPA-Induced Dyskinesia in Parkinson’s Disease

    Philippe Huot, Tom H. Johnston, James B. Koprich, Susan H. Fox and Jonathan M. Brotchie

    David R. Sibley, ASSOCIATE EDITOR, Toronto Western Research Institute, University Health Network, Toronto, Ontario, Canada (P.H., T.H.J, J.B.K, S.H.F., J.M.B.); and Division of Neurology, Movement Disorder Clinic, Toronto Western Hospital, University Health Network, Toronto, Ontario, Canada (P.H., S.H.F.)

    Pharmacological Reviews January 2013, 65 (1) 171-222; DOI: https://doi.org/10.1124/pr.111.005678

  • Regulation of µ-Opioid Receptors: Desensitization, Phosphorylation, Internalization, and Tolerance

    John T. Williams, Susan L. Ingram, Graeme Henderson, Charles Chavkin, Mark von Zastrow, Stefan Schulz, Thomas Koch, Christopher J. Evans and MacDonald J. Christie

    Annette C. Dolphin, ASSOCIATE EDITOR, Vollum Institute, Oregon Health Sciences University, Portland, Oregon (J.T.W.); Department of Neurologic Surgery, Oregon Health Sciences University, Portland, Oregon (S.L.I.); School of Physiology and Pharmacology, University of Bristol, Bristol, United Kingdom (G.H.); Department of Pharmacology, University of Washington, Seattle, Washington (C.C.); Psychiatry and Pharmacology, University of California at San Francisco, San Francisco, California (M.v.Z.); Institute of Pharmacology and Toxicology, Jena University Hospital, Friedrich Schiller University Jena, Jena, Germany (S.S.); Institute of Pharmacology and Toxicology, University of Magdeburg, Magdeburg, Germany (T.K.); Hatos Center of Neuropharmacology, University of California at Los Angeles (C.J.E.); and Discipline of Pharmacology, University of Sydney, Sydney, New South Wales, Australia (M.J.C.)

    Pharmacological Reviews January 2013, 65 (1) 223-254; DOI: https://doi.org/10.1124/pr.112.005942

  • Individual Differences and Social Influences on the Neurobehavioral Pharmacology of Abused Drugs

    M. T. Bardo, J. L. Neisewander and T. H. Kelly

    Michael A. Nader, ASSOCIATE EDITOR, Department of Psychology (M.T.B.), Center for Drug Abuse Research Translation (M.T.B., T.H.K.), and Department of Behavioral Science (T.H.K.), University of Kentucky, Lexington, Kentucky; and School of Life Sciences, Arizona State University, Tempe, Arizona (J.L.N.)

    Pharmacological Reviews January 2013, 65 (1) 255-290; DOI: https://doi.org/10.1124/pr.111.005124

  • Targeted Drug Delivery to Treat Pain and Cerebral Hypoxia

    Patrick T. Ronaldson and Thomas P. Davis

    David R. Sibley, ASSOCIATE EDITOR, Department of Medical Pharmacology, College of Medicine, University of Arizona, Tucson, Arizona

    Pharmacological Reviews January 2013, 65 (1) 291-314; DOI: https://doi.org/10.1124/pr.112.005991

  • Strategies to Address Low Drug Solubility in Discovery and Development

    Hywel D. Williams, Natalie L. Trevaskis, Susan A. Charman, Ravi M. Shanker, William N. Charman, Colin W. Pouton and Christopher J. H. Porter

    Arthur Christopoulos, ASSOCIATE EDITOR, Drug Delivery, Disposition and Dynamics (H.D.W., N.L.T., W.N.C., C.J.H.P.), Centre for Drug Candidate Optimisation (S.A.C.), and Drug Discovery Biology (C.W.P.), Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, Victoria, Australia; and Pfizer Global Research and Development, Groton Laboratories, Groton, Connecticut (R.M.S.)

    Pharmacological Reviews January 2013, 65 (1) 315-499; DOI: https://doi.org/10.1124/pr.112.005660

IUPHAR Nomenclature Report

  • International Union of Basic and Clinical Pharmacology. LXXXVII. Complement Peptide C5a, C4a, and C3a Receptors

    Andreas Klos, Elisabeth Wende, Kathryn J. Wareham and Peter N. Monk

    Pharmacological Reviews January 2013, 65 (1) 500-543; DOI: https://doi.org/10.1124/pr.111.005223

Erratum

  • Correction to: “A Modern Understanding of the Traditional and Nontraditional Biological Functions of Angiotensin-Converting Enzyme”

    Pharmacological Reviews January 2013, 65 (1) 544; DOI: https://doi.org/10.1124/pr.111.01er13

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In this issue

Pharmacological Reviews

Vol. 65, Issue 1

1 Jan 2013

  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)

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  • Review Articles
  • IUPHAR Nomenclature Report
  • Erratum
  • Nitric oxide: physiology, pathophysiology, and pharmacology.

  • The Glutamate Receptor Ion Channels

  • Glutamate Receptor Ion Channels: Structure, Regulation, and Function

  • Receptors for Purines and Pyrimidines

  • Evolving Concepts in G Protein-Coupled Receptor Endocytosis: The Role in Receptor Desensitization and Signaling

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Pharmacological Reviews: 65 (1) (2024)

FAQs

How do I pass a pharmacology test? ›

How to Memorize for Pharmacology
  1. Study early. Study often. ...
  2. Use different activities to summarize and supplement what you've learned. Remember those learning styles we talked about? ...
  3. Quiz yourself! ...
  4. Break down medications by class. ...
  5. Use mnemonics and acronyms. ...
  6. Make flashcards.
May 13, 2024

How to pass the pharmacology hesi? ›

The Do's and Dont's for HESI Pharmacology Practice Exam
  1. Use Generic Name. To study pharmacology more efficiently, prioritize understanding the prefixes and suffixes associated with drug names and their classification. ...
  2. Use Flashcards. ...
  3. Take timed HESI Pharmacology Practice Exams. ...
  4. Don't Cram.

How to study pharmacology easily? ›

10 tips for learning pharmacology
  1. Do the work! “There is no secret. ...
  2. Start with the mechanism of action. “Start with the body's responses and learn the drugs that do them. ...
  3. Flashcards, notecards, and dry erase boards. ...
  4. Understand the big picture. ...
  5. Create study aids. ...
  6. 30-second drug guide lookup. ...
  7. Touch the meds. ...
  8. Constant quizzing.

Is pharmacology hard in nursing school? ›

“It becomes one of the hardest classes for nursing students due to the depth and amount of knowledge needed,” says Megan Lynch, RN and instructor at Pima Community College. Lynch notes that pharmacology is one of the most difficult classes for nursing students, but is essential to patient care.

What percentage of the Nclex is pharmacology? ›

The NCLEX is divided into eight sections: 20% Management of Care; 12% Safety and Infection Control; 9% Health Promotion and Maintenance; 9% Psychosocial Integrity; 9% Basic Care and Comfort; 15% Pharmacological and Parenteral Therapies; 12% Reduction of Risk Potential; and 14% Physiological Adaptation.

Is pharmacology very hard? ›

Pharmacology is the study of how drugs interact with the body and how the body responds to those drugs. Most students studying to be doctors, nurses, and pharmacists will study pharmacology at some point. Unfortunately, pharmacology is a notoriously difficult subject because there are hundreds of drugs to study.

What is a 75% on the HESI? ›

A candidate who scores between 75% to 80% could potentially pass the math section, depending on the requirements of their program. But this score is average. Finally, a score below 75% means that the candidate has failed and must focus more on studying mathematics before reattempting the HESI A2.

What is the HESI pharmacology score range? ›

The HESI Exit Exam score range is between 0 to 1500. The acceptable HESI score is 850 while the recommended HESI score is 900. You need to earn a minimum score of 850 in order to be considered ready to take the NCLEX licensing exam.

How do I get a high score on the HESI exam? ›

How to Prepare for HESI Exams
  1. Make sure you understand the format, duration and methods of the exam.
  2. Make a study plan. ...
  3. Invest in additional test prep resources.
  4. Organize a study group with your classmates.
  5. Take practice exams.

How do you memorize drugs in pharmacology? ›

6 Tips for Pharmacists to Memorize New Drugs Quickly
  1. Memorize no more than one per day. ...
  2. Repeat what you memorized. ...
  3. Memorize new drugs in order of class. ...
  4. Memorize new drugs with acronyms. ...
  5. Memorize new drugs with picture association. ...
  6. Memorize new drugs with a memory palace (advanced technique)
May 10, 2017

Is pharmacology mostly memorization? ›

One study aid for medical students advises that “even though your profs may tell you otherwise, pharmacology is 'pure memorization. '” The discipline is the “ultimate challenge in medical memorization” and one for which some “remedy to dull the pain” of the subject is needed.

Is pharmacology harder than anatomy? ›

While opinions vary, I believe pharmacology is harder than anatomy in nursing school. However, because anatomy teaches the foundations of the structure of the body, you must have a clear understanding of anatomy before you can apply the concepts of pharmacology.

Do a lot of nursing students fail pharmacology? ›

Our nursing pharmacology course under LBL recorded a high failure rate of 37.8% and marginal passing scores across five cohorts (n = 849 students).

What is the hardest test in nursing? ›

Passing the NCLEX is essential to begin your nursing career, but it is also one of the most challenging exams you will ever take. The NCLEX is designed to test your critical thinking skills and your ability to make decisions in high-pressure situations.

How do you memorize pharmacology as a nurse? ›

One of the best ways to study pharmacology is to create mnemonics, funny phrases, and stories. Putting these medications in a story format will help you better remember them come test time. Pharmacology made easy is an excellent book that is a great resource.

What is the fastest way to memorize pharmacology drugs? ›

Easy Way to Memorize Medications For Your PTCB Exam
  1. USE A DRY-ERASE BOARD/FLASHCARDS/NOTECARDS.
  2. CROSSWORD PUZZLES.
  3. ACRONYM FOR DRUG NAMES.
  4. STUDY CHART.
  5. CONSTANT QUIZZING WITH STUDY BUDDY.
  6. JINGLE OR RHYME.
  7. PRACTICE.
  8. TOUCH THE MEDICINES.

What is the first pass in pharmacology? ›

The first-pass metabolism or the first-pass effect or presystemic metabolism is the phenomenon which occurs whenever the drug is administered orally, enters the liver, and suffers extensive biotransformation to such an extent that the bioavailability is drastically reduced, thus showing subtherapeutic action (Chordiya ...

What is the best way to take pharmacology notes? ›

Using flashcards is one of the most effective ways to study pharmacology. You can purchase pre-made online/digital note cards including LevelUp RN, or Nurse in the Making. An even better option is to make them yourself.

How do you get a good grade in pharmacology? ›

Student Blogs
  1. Make drug cards for each drug or a drug card for each drug classification. ...
  2. Try to study the classifications of medications instead of studying each drug. ...
  3. Understand that the medications in the same classifications share many of the same characteristics (I.e., adverse effects).

References

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